The most renowned filmmaker of his era, Martin Scorsese virtually defined the state of modern American cinema during the 1970s and '80s.

Scorsese was born on November 17, 1942, in Flushing, NY. The second child of Charles and Catherine Scorsese -- both of whom frequently made cameo appearances in their son's films -- he suffered from severe asthma, and as a result was blocked from participating in sports and other common childhood activities. Consequently, Scorsese sought refuge in area movie houses, quickly becoming obsessed with the cinema, in particular the work of Michael Powell. Raised in a devoutly Catholic environment, he initially studied to become a priest. Ultimately, however, Scorsese opted out of the clergy to enroll in film school at New York University, helming his first student effort, What's a Nice Girl Like You Doing in a Place Like This?, a nine-minute short subject, in 1963.